Each breakthrough demanded more sophisticated coordination of HER2-positive disease management. Trastuzumab needed cardiac monitoring. CLEOPATRA required combination precision.
Today's advanced immunotherapies demand genetic confirmation, toxicity protocols, and brain monitoring across several specialists.
The treatments changed.
The infrastructure did not.
The science evolved. The coordination infrastructure did not. What held the system together was absorbed by the people closest to the gaps.
It runs on informal knowledge, personal relationships, and workarounds accumulated over years. It has no job description. It has no dataset.
The Six Dimensions Framework names where that coordination lives and where it breaks.
Learn more about why now →